Dr. Edwin P. Ewing, Jr.

This micrograph depicts the histopathologic changes found in a biopsied lymph node indicative of a Kaposi’s sarcomatous lesion from a patient with Acquired Immunodeficiency Syndrome, also known as AIDS.

Kaposi’s sarcoma is a cancer of connective tissues such as cartilage, bone, fat, muscle, and blood vessel. The vast majority of Kaposi’s sarcoma cases have developed in association with human immunodeficiency virus (HIV) infection, and the acquired immunodeficiency syndrome (AIDS). The histopathology revealed in this slide includes characteristic erythrocyte-filled, slit-like spaces, and occasional cells containing globules.